Groupleader: Jean-Paul COUTELIER
Email: coutelier
mexp.ucl.ac.be
website: www.icp.ucl.ac.be/mexp/
contact: MEXP
Avenue Hippocrate 74 UCL 74.30
B-1200 BRUXELLES
Tel: +32 2 764.65.29
Fax: +32 2 764.74.30
MEXP Unit Directory (People)
Research interest
Antiviral Immunity and Pathogenesis: The possibility for evoluted organisms to survive viral infections depends on the ability of their immune system to eliminate the infectious agent. Therefore, numerous mechanisms, involving different types of immune cells such as cytolytic lymphocytes, T helper and B lymphocytes and macrophages, the molecules that allow those cells to communicate, namely the lymphokines, and the products of those interactions, including antibodies, have been elaborated. On the other hand, viruses have developed strategies to escape the immune system of their hosts, such as frequent mutations or latency, or even to impair this system, which often leads to diseases such as autoimmunity or immune deficiencies. Our project is to investigate, in murine models, some aspects of these relations between viruses and the immune system.