Louis HUE, MD, PhD

Curriculum Vitae

Belgian, born in Namur (Belgium), September 15, 1943

Degrees:

• 1967: M.D. Louvain University  Medical School, Summa cum Laude.
• 1979: Agrégé de l'Enseignement Supérieur (corresponding to a PhD degree) Louvain University Medical School.

Postgraduate experience

• 1967-1979: Research Fellow and Senior Research Associate of the FNRS, Laboratoire de Chimie Physiologique (Prof. H.G. Hers & Prof. C. de Duve), Louvain University Medical School and International Institute of Cellular and Molecular Pathology, (ICP) Brussels, Belgium.
• 1980-1981:   Visiting Scientist in the Department of Physiology (Prof. J.H. Exton), Vanderbilt University, Nashville, USA.
• 1982-present: Senior Investigator, Hormone and Metabolic Research Unit, Louvain University  Medical School and ICP, Brussels, Belgium.

Appointments

• 1967-1979: Research fellow of the FNRS, Belgium
• 1988-present: Full Professor of Biochemistry at the University of Louvain
• 1989-1994: Chairman, Department of Biochemistry and Cell Biology
• 2004-present: Head, Hormone and Metabolic Research Unit, University of Louvain and ICP.

Research activities and scientific achievements

General theme of research: regulation of carbohydrate and lipid metabolism in mammalian tissues.

Demonstration of the role of futile cycles in the control of liver gluconeogenesis. Discovery of fructose 2,6-bisphosphate (with E. Van Schaftingen and HG Hers). Discovery of two genes coding for PFK-2/FBPase-2, the bifunctional enzyme responsible for the synthesis and degradation of fructose 2,6-bisphosphate (with G. Rousseau). Discovery of new targets for AMPK (with M.H. Rider). Discovery of the anabolic response of the liver to cell swelling.
Publication of more than 180 research papers in peer-reviewed journals.

Research awards

• Rik and Nel Wouters Award 1991 (shared with G. Rousseau)
• Upjohn Award 1992 (shared with K. Veitch)
• Therabel Award, 1997
• Professeur Lucien Dautrebande Prize, 1997 (shared with G. Rousseau)

Other activities and honors

Scientific advisor for the INSERM and CNRS (France); past editor for the Biochemical Journal and the European Journal of Biochemistry; Fellow of the Royal Academy of Medicine of Belgium.